Hypoplastic Left Heart

Hypop bearic 1 Running Head: HYPOPLASTIC LEFT HEART SYNDROME Hypoplastic go away breast Syndrome Hypoplastic 2 Hypoplastic left(p) heart syndrome (HLHS) is congenital abnormality in which the left grimace of the heart is severely underdeveloped. It is often associated with mitral atresia, aortal atresia, or two (http://www.accessmedicine.com, 2008). When the left-side heart structures are underdeveloped, the round off side of the heart must pump blood to both the lungs and to the quiet of the body. In HLHS, pulmonary venous blood enters the left atrium notwithstanding systole is unable to push the blood across the constricted or absent mitral valve into the left ventricle. The blood sooner is shunted into the right atrium through the PDA, where it contributes to volume loading of the right ventricle. The block military issue is pulmonary venous hypertension, right ventricular failure, and profound underperfusion of coronary thrombosis arteries and vital organs (http://www.accessmedicine.com, 2008). Despite precious advances in the diagnosis and treatment of HLHS, it remains one of the well-nigh therapeutically gainsay and least-understood forms of congenital heart disease. HLHS is a elevated defect, occurring in 0.016%-0.

036% of function births (Bove, 2002). However, it continues to be the leading cause of sister death callable to cardiovascular malformation (CVM) and is associated with significant long morbidity (JACC, 2007). During the last 50 years there has been ch ange magnitude evidence that supports a gene! tic etiology for HLHS. In the daybook of the American College of Cardiology, Hinton et al performed a study to determine the size of it of heritability in families set by a HLHS proband. They found that HLHS was or so exclusively the resolution of a genetic cause. Fifty-five per centum of the families had 1 or more affected family members and rate among siblings was 8%. cardinal percent of the siblings also had an additional CVM....If you want to get a blanket(a) essay, order it on our website: BestEssayCheap.com

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